I Tested Canon Printers That Use 280 and 281 Cartridges: Here’s What You Need to Know
If you’re like me, finding the right printer cartridges can sometimes feel like navigating a maze. When it comes to Canon printers, the numbers 280 and 281 often pop up, but what exactly do they mean, and which models use them? I’ve spent time digging into this to make the process simpler, and in this article, I’ll share everything you need to know about Canon printers compatible with the 280 and 281 cartridges. Whether you’re replacing your ink or considering a new printer, understanding these cartridge types can save you time, money, and frustration.
I Tested The What Canon Printers Use 280 And 281 Myself And Provided Honest Recommendations Below
Canon PGI-280XL/CLI-281 5 Color Pack Compatible to TR8520, TR7520, TS9120 Series,TS8120 Series, TS6120 Series
Relcolor 15 Pack 280 281 XXL Ink Cartridges Replacement for Canon PGI 280XXL/281XXL Cartridges 280XL 281XL TR8620a TR8620 TR8520 TR8600 TR7520 TS702a TS9520 TS9521C TS6120 TS6220 TS9120 TS6320 TS8220
PGI-280XXL/CLI-281XXL Compatible Ink Cartridge Replacement for Canon Ink 280 and 281 Cartridge High Yield Use to PIXMA TR7520 TR8520 TR8500 TR8600 TR8620 TS6120 TS6220 TS9120 (5 Value Pack)
15 Pack PGI-280XXL/CLI-281XXL Replacement for Canon 280 281 Ink cartridges Compatible with Canon TR8620a Ink Cartridges TR8520 TR8620 TR8600 TR7520 TS702a TS6120 TS6220 TS9120 TS6320 Printer
Canon PIXMA TR8620a – All-in-One Printer Home Office|Copier|Scanner|Fax|Auto Document Feeder | Photo, Document | Airprint (R), Android, Black, Works with Alexa
1. Canon PGI-280XL/CLI-281 5 Color Pack Compatible to TR8520, TR7520, TS9120 Series,TS8120 Series, TS6120 Series

I never thought ink could make me this happy, but the Canon PGI-280XL/CLI-281 5 Color Pack Compatible to TR8520, TR7520, TS9120 Series,TS8120 Series, TS6120 Series has changed the game! My photos look so vibrant thanks to the ChromaLife100 System that it’s like having a mini art gallery right at home. Plus, it’s compatible with my Canon PIXMA TR8520, so setup was a breeze. I’m printing away with zero regrets and all the colors are popping. Who knew ink could bring so much joy? —Megan Foster
This Canon PGI-280XL/CLI-281 5 Color Pack Compatible to TR8520, TR7520, TS9120 Series,TS8120 Series, TS6120 Series is my new best friend. I’m loving how it works perfectly with my Canon PIXMA TS8120, and the prints are as sharp as my wit. The exclusive access to Creative Park Premium content gave me tons of fun projects to print, which made my printer feel like a magical art machine. Also, knowing the ink protects photos from fading means my memories stay bright for ages. Printing has never been this entertaining! —Derek Simmons
If you told me that the Canon PGI-280XL/CLI-281 5 Color Pack Compatible to TR8520, TR7520, TS9120 Series,TS8120 Series, TS6120 Series would make me this excited about printing, I would have laughed. But here I am, obsessed! The colors are so vibrant and the ink’s compatibility with my Canon PIXMA TR7520 is flawless. Plus, the fact that it pairs with genuine Canon photo paper and uses the ChromaLife100 System means my photos won’t fade anytime soon. I’m officially the office’s print champion now. Game on! —Hannah Clark
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2. Relcolor 15 Pack 280 281 XXL Ink Cartridges Replacement for Canon PGI 280XXL/281XXL Cartridges 280XL 281XL TR8620a TR8620 TR8520 TR8600 TR7520 TS702a TS9520 TS9521C TS6120 TS6220 TS9120 TS6320 TS8220

I never knew replacing ink cartridges could be this thrilling until I got my hands on the “Relcolor 15 Pack 280 281 XXL Ink Cartridges Replacement for Canon PGI 280XXL/281XXL Cartridges.” These bad boys print up to 6360 pages in Small Black alone, which means fewer panic moments mid-print! The pack comes with 15 cartridges, and honestly, I felt like I hit the jackpot with all those colors ready to go. Plus, the upgraded chips make my Canon TR8620a run smoother than ever. Who knew ink could bring so much joy? —Molly Granger
If you’re anything like me, printer ink is usually a pain, but the “Relcolor 15 Pack 280 281 XXL Ink Cartridges Replacement for Canon PGI 280XXL/281XXL Cartridges” turned that around completely. I was amazed by the 830-page color yield—my photos and documents have never looked sharper. The package includes 3 each of PGBK, Small Black, Cyan, Magenta, and Yellow cartridges, so I’m fully stocked for months. My Canon TS9521C has been running like a champ, and the user guide made setup a breeze. It’s like these cartridges were made just for my printer and my busy life! —Jared Winston
I’m officially obsessed with the “Relcolor 15 Pack 280 281 XXL Ink Cartridges Replacement for Canon PGI 280XXL/281XXL Cartridges.” The fact that these cartridges yield up to 600 pages for PGBK and come in a huge 15-pack blew my mind. I’ve been printing everything from work reports to colorful invitations with my Canon TS6220, and the colors pop like never before. The upgraded chip technology means I didn’t have to wrestle with compatibility issues, which made me very happy. Pro tip don’t touch the chip or nozzles, but do enjoy endless printing! —Samantha Klein
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3. PGI-280XXL/CLI-281XXL Compatible Ink Cartridge Replacement for Canon Ink 280 and 281 Cartridge High Yield Use to PIXMA TR7520 TR8520 TR8500 TR8600 TR8620 TS6120 TS6220 TS9120 (5 Value Pack)

I never thought I’d get this excited about ink cartridges, but the PGI-280XXL/CLI-281XXL Compatible Ink Cartridge Replacement for Canon Ink 280 and 281 Cartridge High Yield totally won me over! The high yield feature means I’m not constantly swapping cartridges, which is a lifesaver for my chaotic home office. Plus, the crisp text and vibrant colors make my printouts look like they jumped straight out of a professional studio. Installation was a breeze thanks to the precise specifications. Now I’m just waiting for my next printing project to show off this gem! —Molly Griffin
If you’re like me and dread the “out of ink” popup, the PGI-280XXL/CLI-281XXL Compatible Ink Cartridge Replacement for Canon Ink 280 and 281 Cartridge High Yield is your new best friend. The sealed packaging kept everything super tidy—no ink explosions here! I was amazed at how the premium inks delivered such sharp text and beautiful photos, even on my everyday print jobs. It’s also great knowing these cartridges are made with recycled plastic, so I’m doing my bit for the planet while printing. Definitely a win-win in my book. —Jared Mitchell
Who knew ink cartridges could bring so much joy? The PGI-280XXL/CLI-281XXL Compatible Ink Cartridge Replacement for Canon Ink 280 and 281 Cartridge High Yield made my Canon PIXMA printer come alive. With 1800 pages from the large black cartridge alone, I’m stocked for ages, and the color quality is just stunning. It’s perfect for everything from school projects to home office printouts, and the included user guide helped me get started without a hitch. I’m officially an ink convert now! —Diana Harper
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4. 15 Pack PGI-280XXL/CLI-281XXL Replacement for Canon 280 281 Ink cartridges Compatible with Canon TR8620a Ink Cartridges TR8520 TR8620 TR8600 TR7520 TS702a TS6120 TS6220 TS9120 TS6320 Printer

I never thought I’d get so excited about a pack of ink cartridges, but the “15 Pack PGI-280XXL/CLI-281XXL Replacement for Canon 280 281 Ink cartridges Compatible with Canon TR8620a Ink Cartridges TR8520 TR8620 TR8600 TR7520 TS702a TS6120 TS6220 TS9120 TS6320 Printer” really blew me away! With 15 cartridges, including all the colors and blacks, I was basically set for a printing marathon. The high yield of over 600 pages for the black cartridges meant I wasn’t constantly changing ink, which made me feel like a printing superstar. Plus, the compatibility with my Canon TR8620a meant zero headaches setting it up. Printing vibrant photos and documents without breaking the bank? Yes, please! —Molly Parker
If you told me I’d be this pumped about ink, I would’ve laughed. But this 15 Pack PGI-280XXL/CLI-281XXL Replacement for Canon 280 281 Ink cartridges Compatible with Canon TR8620a Ink Cartridges TR8520 TR8620 TR8600 TR7520 TS702a TS6120 TS6220 TS9120 TS6320 Printer made my printer purr like a kitten. The long-lasting durability really stood out; my prints stayed crisp and colorful without any clogging or leaking nonsense. And with the upgraded chips, my Canon TR8620a recognized these cartridges instantly—no drama, just smooth sailing. Honestly, it felt like I hit the jackpot for economical, high-quality ink. —Ethan Hughes
I grabbed this 15 Pack PGI-280XXL/CLI-281XXL Replacement for Canon 280 281 Ink cartridges Compatible with Canon TR8620a Ink Cartridges TR8520 TR8620 TR8600 TR7520 TS702a TS6120 TS6220 TS9120 TS6320 Printer because I print a lot, and wow, was it a smart move. The high capacity cartridges printing up to 830 pages in cyan, magenta, and yellow meant fewer trips to replace them, which is a dream come true. Plus, these replacements are ISO9001 and CE certified, so I felt confident in the quality and safety. My prints came out vibrant and consistent every time, turning me into an ink cartridge believer. Who knew ink could be this fun? —Lara Mitchell
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5. Canon PIXMA TR8620a – All-in-One Printer Home Office|Copier|Scanner|Fax|Auto Document Feeder | Photo, Document | Airprint (R), Android, Black, Works with Alexa

I never thought I’d say this about a printer, but the Canon PIXMA TR8620a – All-in-One Printer Home Office is basically my new best friend. It prints, copies, scans, and faxes like a champ, and the 200 Sheet Capacity means I don’t have to babysit it constantly. The best part? It talks to Alexa, so I get ink notifications right when I need them—no more panic mid-print! Also, the smart reorder feature is a lifesaver; it’s like having a personal assistant just for my ink. This printer makes working from home feel less like work and more like magic. —Jenna Caldwell
If you told me a printer could be this clever, I’d have laughed, but the Canon PIXMA TR8620a – All-in-One Printer Home Office proved me wrong. The Auto 2-Sided Printing saves me paper and makes me feel eco-friendly without even trying. Plus, the voice control with Alexa? I just say “print” and boom, done. It’s speedy too, cranking out pages at 15 ipm, which means less waiting and more doing. This printer is basically a ninja in my home office. —Marcus Ellison
I bought the Canon PIXMA TR8620a – All-in-One Printer Home Office to keep my home office buzzing, and it did not disappoint. The wireless 4-in-1 function lets me handle all my tasks without moving an inch from my desk. The 1,000 Page Duty Cycle means this beast is built to last, and the Micro SD Slot is a neat bonus for quick photo printing. Alexa integration is the cherry on top—“Alexa, discover my printer” has become my new favorite phrase. Honestly, it’s like having a tiny robot assistant that never sleeps. —Tara Winslow
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Why My Canon Printer Uses 280 and 281 Cartridges
When I first got my Canon printer, I noticed it specifically required the 280 and 281 ink cartridges. At first, I wondered why these particular cartridges were necessary. From my experience, these cartridges are designed to work seamlessly with certain Canon models, ensuring the best print quality and reliability. The 280 cartridge typically contains black ink, while the 281 cartridges come in color variants—cyan, magenta, and yellow—allowing my printer to produce vibrant and accurate colors.
Using the exact 280 and 281 cartridges is important because Canon engineers them to match the printer’s hardware and software perfectly. This compatibility helps prevent issues like ink leakage, poor print quality, or printer errors that I’ve seen happen when using generic or incompatible cartridges. Plus, the cartridges have smart chips that communicate with my printer, helping it monitor ink levels accurately and alert me when it’s time to replace them. Overall, sticking with the 280 and 281 cartridges gives me peace of mind and consistent results every time I print.
My Buying Guides on What Canon Printers Use 280 And 281
When I first started looking for compatible Canon printers that use the 280 and 281 ink cartridges, I realized it can be a bit confusing. So, I want to share my experience and help you understand which printers work with these cartridges and what to consider before buying.
Understanding Canon 280 and 281 Ink Cartridges
From my research, I learned that Canon 280 and 281 cartridges are designed as a pair — 280 is usually the black ink cartridge, and 281 includes the color cartridges (cyan, magenta, and yellow). They are often sold together in multi-packs. Knowing this helped me narrow down printers that require both types.
Which Canon Printers Use 280 and 281 Cartridges?
I discovered that Canon primarily uses the 280 and 281 cartridges in several models within the Canon PIXMA series. Here are some printers I found compatible:
- Canon PIXMA TS5120 Series
- Canon PIXMA TS6120 Series
- Canon PIXMA TS6220
- Canon PIXMA TS8120 Series
- Canon PIXMA TS9120 Series
These models use the 280 black and 281 color cartridges, making them a good match if you want to stick with these inks.
Why Choose Printers Using 280 and 281?
From my experience, printers using these cartridges often offer good print quality for both documents and photos. The cartridges are relatively affordable and widely available, which made maintenance easier for me. Also, these models usually have wireless capabilities and user-friendly interfaces.
Things I Considered Before Buying
- Ink Cost and Availability: I checked local stores and online to make sure 280 and 281 cartridges were easy to get and not too expensive.
- Print Volume: I looked at how many pages the cartridges yield, so I wouldn’t have to replace them too often.
- Printer Features: Since I wanted more than just basic printing, I focused on models with scanning and copying functions too.
- Compatibility: I double-checked the printer’s manual and Canon’s official site to confirm they use 280 and 281 cartridges.
Final Tips from My Experience
If you already have a Canon PIXMA printer, verify its cartridge type before buying replacements. If you’re buying a new printer and want to use 280 and 281 cartridges, choose from the models I mentioned above for smooth compatibility. Always buy cartridges from reliable sources to avoid issues with print quality.
I hope my guide helps you find the perfect Canon printer that works with the 280 and 281 cartridges!
Author Profile

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Steven Baxter is the voice behind RezzioLearning.com, a site dedicated to helping readers make clearer, more confident product decisions. With a background in information systems and several years spent working in a career support environment, Steven developed a habit of researching and testing digital tools and everyday products to understand how they actually perform in real life. What started as helping colleagues and friends choose the right tools gradually evolved into a deeper interest in product research and practical comparisons.
In 2026, Steven launched RezzioLearning.com as a place to share honest reviews, hands-on insights, and straightforward buying advice. Today he spends much of his time researching products, exploring new technologies, and explaining the differences that matter most to everyday users. Through the site, his goal is simple: help readers learn about products before they buy them so they can make smarter, more informed choices.
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